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Description
doi: 10.1016/j.freeradbiomed.2012.11.003
Normally, M2 macrophages are involved in tissue repair, but in the context of IPF, they become profibrotic by secreting cytokines and growth factors such as Transforming Growth Factor-beta (TGF-\(\beta\)) and Platelet-Derived Growth Factor (PDGF)
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Limitations include small cohorts, short follow-up, heterogeneous peptide types and doses, and mixed endpoints
