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AEs = Adverse Events related to treatment
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VEGF-A and related family members have well-documented neuroprotective actions in the retinapromoting retinal ganglion cell survival, Mller-cell viability, and production of neurotrophic factors via VEGFR2 PI3KAkt signalingso prolonged suppression could, in principle, reduce endogenous neurotrophic support (Nishijima et al., 2007
Most individuals with NAFLD present with comorbid metabolic abnormalities such as obesity, IR, dyslipidaemia, and hypertensioncollectively described as metabolic syndrome [13]
