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this fraction thus escapes processing but also undergoes increased endosomal pathway-mediated degradation, resulting in circulating hyperproinsulinemia in a mouse model
6 Metallomics and omics synergies in the study of metal mixture effects on human disease pathways The emerging fields of metallomics and the metallome represent powerful frameworks for understanding the complex biological effects of metal exposures, particularly in the context of environmental co-exposures
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doi: 10.1158/0008-5472.CAN-06-0300
