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DUrso G, Thomann A, Anzures-Cabrera J, Zinnhardt B, Ricci B, Bailey L, et al

Correspondingly, disturbance in the gut microbiota can lead to functional impairments in the digestive system, resulting in spleen deficiency syndrome [84]

90,91 Several ethnobotanical reports also document lesser-known species used by tribal populations for GI care, such as Ardisia solanacea , Psidium guajava , Achyranthes bidentata , Turnera diffusa , and Phoradendron californicum -employed in forms like leaf juice or infusions for treating ulcers, acidity, diarrhea, and dysentery

Compared to molecules that are randomly distributed in the cytoplasm, drug molecules concentrated in subcellular compartments are more difficult to excrete, which improves the bioavailability of drugs while reducing the development of drug resistance [82, 83]