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Description
MOTS-c triggers the same cellular response as an endurance session shifting metabolism toward fat oxidation

& Perveen, S

This can create a physiologic amplification loop: Estrogen increases histamine release Histamine increases estrogen signaling Increased estrogen further activates mast cells Histamine burden escalates further This may partially explain why histamine intolerance symptoms often worsen during hormonal fluctuations, estrogen dominance patterns, or perimenopause transitions

Recent insights on the genetics and epigenetics of endometriosis
