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The clinical applications of IGF-1 LR3 span across various growth deficiencies and conditions requiring anabolic support, including hormone deficiencies leading to short stature, Turner Syndrome, muscle-wasting diseases, and conditions associated with pituitary tumors

After 24 h of treatment, a large part of the cells fluoresced, showing active caspase and triggering cell death, according to the FLICA test, which was used to identify cell apoptosis

4.2 Negative implication As previously described, ROS in plants at low or moderated intensities function as signalling molecules in the regulation of normal plant growth as well as in acclimation under stressful conditions