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These neurons modulate food intake, energy expenditure, and reproduction (60)

Studies have reported that alterations in the gut microbiome, characterized by changes in microbial diversity and imbalances in key microbial taxa, are observed in patients with depression [30]

In a rat model of PD induced by 6-OHDA, 7-HMR treatment did not significantly prevent the loss of nigral dopaminergic neurons, but it produced notable anti-inflammatory effects in the brain (56)

[DOI] [PMC free article] [PubMed] [Google Scholar] 118.Wei G, Wang D, Lu H, Parmentier S, Wang Q, Panter SS, et al