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HUBERMAN: It can release epithelium
Although this adaptation is beneficial in hypoxia, it is deleterious when RBCs are challenged by oxidant stress, such as during refrigerated storage in the blood bank [103] or in sickle cell disease, where deoxy-sickle hemoglobin stabilization further promotes its crystallization [102]
Its defined peptide structure and copper coordination properties make it suitable for standardized analytical studies and repeatable experimental workflows
