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In addition to sugars or artificial sweeteners, many CSDs contain caffeine, which acts as a mild stimulant

3 Microbial-host interplay in TMAO synthesis and metabolism TMAO originates from dietary precursors metabolized through a tightly coordinated interplay between gut microbiota and host hepatic enzymes (50)

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The amount of free cyanide released during cyanocobalamin metabolism is far below any toxicologically significant level
