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The dysregulation of iron metabolism is a hallmark of various cancers, contributing to tumor progression, metastasis, and notably, drug resistance
doi: 10.1016/S0140-6736(16)30173-8 298 MatchamFRaynerLSteerSHotopfM

J Chem Soc Trans 65:899910 Finkel T, Holbrook NJ (2000) Oxidants, oxidative stress and the biology of aging

In invertebrates, there is only one FOXO gene, termed dFOXO in the fruit fly and daf-16 in the worm
