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Given that we know BrAC is a point of care test, operators should be aware of these limitations in accuracy and potential for erroneous readings
It was demonstrated that phosphorylation at the Ser637 site stimulates Ser616 phosphorylation and that only the inhibition of downstream Ser616 phosphorylation results in mitochondrial elongation (Gonzalez et al., 2021)
10.1136/thx.2007.086199
The production of ROS is the result of these functional abnormalities in mitochondria
