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demonstrated that in HepG2 cells, L-carnitine acts as an endogenous histone deacetylase inhibitor, promoting p21Cip1 expression ( In addition, a rat hepatitis-HCC model suggested that L-carnitine might mitigate processes associated with hepatocarcinogenesis, such as oxidative stress, and improve mitochondrial function ( The potential tumor-suppressive effects of L-carnitine provide a unique chemopreventive perspective for long-term MASLD management

doi: 10.1007/s10863-016-9678-4

Int J Neuropsychopharmacol 24(4):256313
