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The neurobiology of epilepsy

Preclinical research has investigated Orexin-B in the context of narcolepsy models, vigilance state regulation, autonomic modulation, and neuroendocrine signaling

From the computed pKa values, we obtained relative proton solvation energies, which agree very well with the proton solvation energies computed recently by ab initio methods, and used these energies in the present study
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