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Autophagy plays a critical role in regulating EMT by degrading cellular damage-associated factors, thereby maintaining epithelial homeostasis and inhibiting mesenchymal transition

Interestingly, the first step in de novo pyrimidine biosynthesis mediated by CPSs occurs mainly in mitochondria via CPS1 in K-Ras/LKB1-mutant lung cancer cells 32 (Fig

.,Georgiou-SiafisSKTsiftsoglouASThe key role of GSH in Keeping the Redox Balance in Mammalian Cells: Mechanisms and significance of GSH in detoxification via formation of conjugates.2023;12(11):1953

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