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However, the polyArg-tag/cation-exchange resins affinity pair shows low selectivity and the tag promotes aggregation of the protein due to chargecharge interactions (Hedhammar et al., 2005)

Pathogenic mechanisms of autoantibodies in autoimmune diseases include interaction with cell surface receptors, cell surface binding and lysis, immune complex-mediated damage, binding to extracellular molecules, and autoantibody transfer across the placenta [321]

doi: 10.1517/17425247.2013.860131

182 Not all instances of NET development result in neutrophil death following the extracellular release of DNA
