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In a different multicenter, randomized, double-blind, placebo-controlled trial, Ziegler and co-workers examined the effects of ALA on neuropathic deficits and positive sensory symptoms in patients with diabetes with distal symmetric polyneuropathy [76]

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Through deacetylating CPT2, SIRT3 alters cellular metabolic phenotype to be more reliant on FAO, thereby contributing to the accumulation of LC and reduction of PC

Our findings clearly indicate that co-treatment with tobramycin in the presence of pyruvate-depleting conditions, rendered the antibiotic tobramycin more effective in killing biofilm cells