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1 Introduction Epilepsy is a common disorder of the central nervous system (CNS), characterized not only by recurrent epileptic discharges but also by frequent and severe neuropsychiatric comorbidities, with depression being the most prevalent (Vayanakkan et al., 2024)

VaD is ranked as the second most common dementia subtype, following Alzheimers disease (AD) (Morgan and Mc, 2024)

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Taguchi K, Yamamoto M (2020) The KEAP1-NRF2 system as a molecular target of cancer treatment
