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(77) reported a decrease in the gene expression of MMP-2 and MMP-9 alongside an increase in TIMP1 expression in murine skin exposed to UVB radiation when 20 mg/kg areca nut PCs were orally administered to mice, indicating their ability to mitigate collagen degradation and slow photoaging effects on the skin through the inhibition of the MAPK signaling pathway
It also includes ginkgo biloba, commonly used in cognitive supplements to support blood flow to the brain and glutamine, an amino acid involved in normal protein metabolism
Hohol, M
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