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methimazole Methimazole Trade Name: Tapazole Drug Class: Antithyroid (Thioamide) Mechanism of Action: ~10 times more potent than propylthiouracil (PTU) inhibits thyroid hormone synthesis methimazole inhibits the thyroid enzyme thyroid peroxidase, also called iodide peroxidase, or thyroperoxidase (TPO)

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[13] [15] The frequency and severity of side effects are influenced by the dose, route of administration, and individual patient factors

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