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223,224 The most widespread modification methods include backbone, ribose, and nucleobase modifications

doi: 10.1007/s11011-019-00519-9 487 ChatterjeeKMukherjeeSVanmanenJBanerjeePFataJE

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In another trial, full-body resistance training for 10 weeks also led to increased NAD + , NADH levels, and SIRT activity in muscle 329