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This regenerative process is driven by adult multipotent OPCs that proliferate and migrate from their niches to damaged sites, differentiating into mature oligodendrocytes that produce new myelin sheaths (reviewed by (Dimou & Gallo, 2015
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This pragmatic, oncology-specific rationale underpins the current algorithm, designed to optimize blood pressure control while accounting for disease severity, particularly in higher-risk cohorts within the prospective study population
The mechanism was suggested to occur at a post-transcriptional or translational step of collagen biosynthesis, though this remains to be confirmed
