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Nature (2015) 520(7545):5762.10.1038/nature14344 78 GaglioDSoldatiCVanoniMAlberghinaLChiaradonnaF

Conforti, F

Probiotics, prebiotics, and synbiotics have exhibited effectiveness in modulating immune responses, treating infections, managing inflammatory bowel diseases, and augmenting cancer treatment modalities [280]

This modification allows for systemic administration, enabling the peptide to reach distant tissues (muscle, heart, nervous system) to activate stem cells and promote tissue repair, overcoming the limitation of native MGF which acts only locally