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Tesamorelin is contraindicated in patients with active malignancy, and adverse effects may include peripheral edema and carpal tunnel syndrome

demonstrated that 2060% of 9(10)-EpODA was converted to 9,10-DiHODA, and 50% of 12-HpODA was degraded, while 12-HODA and 12-oxo-ODA were unaltered

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Several experimental works reported a dampening effect of DSIP on elevated cortisol values and a modulation of the stress axis
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