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Description
Intracellular metabolic processes are essential for maintaining the normal physiological activities of bacteria, and an increasing body of research has demonstrated a significant association between metabolic alterations and the development of drug resistance
Preclinical research efforts should also prioritize the development of patient-derived 3D tumor organoids and xenograft models that faithfully recapitulate CSC heterogeneity and therapy resistance
Other Respir
However, several drugs have been used "off label," including pentoxifylline (PTX) and corticosteroids
