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In 2019, Scarneciu et al., conducted a clinical trial on 30 patients with UTIs, evaluating the efficacy of intravesical instillation of hyaluronic acid in reducing and relieving lower urinary tract irritation symptoms

Heightened serotonin levels can also promote the release of dopamine and norepinephrine, resulting in changes to memory, GI problems, mood, and blood coagulation (436)

The specific neurobiological mechanisms of METH addiction are summarized in Table 1
