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The expression and activity of MLCK1 can be increased by a number of cytokines including TNF- [35,36,37] and IL-1 [38], providing evidence for the role of the immune system signalling in affecting paracellular permeability

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Resveratrol is a polyphenolic stilbenoid found in grapes, pine nuts, peanuts and red wine and shows antioxidant, anti-inflammatory and neuroprotective properties [132, 133]
