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The inflammatory nature of homocysteine and the effects of decreased myelin production before the occurrence of overt demyelination create a sustained low grade inflammatory response with a relative hyperexcitation of the peripheral and central nervous system

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It alleviates pain behavior in diabetic neuropathy, low back pain, neuralgia and promotes nerve conduction

[3] The speed of response depends on multiple factors including the severity and duration of deficiency, the presence of neurological complications, and individual metabolic differences