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Identification of a small molecule that increases hemoglobin oxygen affinity and reduces SS erythrocyte sickling

These amino acids are then used to synthesize new proteins, such as collagen

Abstract Objective: Paclitaxel (PTX), a conventional second-line therapeutic agent for advanced gastric cancer (GC), exhibits compromised clinical efficacy due to acquired chemoresistance in patients, the molecular mechanisms of which remain poorly elucidated

At the C-terminal, the Neh3 domain is involved in the interaction with a transcription coactivator called CHD6 (a chromo-ATPase/helicase DNA-binding protein) in the nucleus