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P2X 1 receptor deficiency is also very rare and contributes to impaired platelet activation under high shear stress but is clinically subtle [90]
A prominent example is the 5 Adenosine Monophosphate-Activated Protein Kinase (AMPK)PGC-1 axis, which responds to shifts in muscle energy status triggered by repetitive contractions
10.3389/fimmu.2022.942768 Front Immunol
Acknowledgments The authors are grateful to Dr
