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Description
According to the American Association of Clinical Endocrinologists the and American College of Endocrinology (AACE/ACE) Obesity Clinical Practice Guidelines, weight loss medications must not be used during pregnancy

Food and Drug Administration (FDA) for human consumption or medical use

(1994, USA) had 13 students change from a lacto-ovo vegetarian to a vegan diet: All 4 with sB12 in the 600-900 range fell to below 500 pg/ml in 2 months

More serious but rare adverse events include pancreatitis (0.2% incidence), gallbladder disease requiring surgical intervention, and medullary thyroid carcinoma risk in genetically predisposed individuals (contraindicated in patients with personal or family history of MTC or MEN2 syndrome)
