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Although Hitrechol QD treatment group showed a trend of decrease compared to vehicle treated group, no statistical difference was found
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427 A preliminary clinical study involving five patients with platinum-resistant high-grade epithelial ovarian cancer receiving a combination of carboplatin and Trientine indicated that Trientine can partially reverse the resistance of cancer cells to platinum therapy, warranting further evaluation in larger studies
Occasional reports of mild side effects, like headaches, also exist, though these are typically manageable
