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For instance, melanotan II, which increases melanin production to darken skin, has been linked to reports of melanoma and concerning changes in existing moles, though a direct causal relationship hasnt been established

These characteristics endow silybin with great potential in treating various diseases through anti-inflammatory, antioxidant, and anticancer mechanisms

This cascade of metabolic dysregulation not only directly induces the phenotype switching of PASMCs from a contractile to a highly proliferative and migratory synthetic phenotype [132] but also causes significant medial wall thickening, ultimately driving PH disease progression

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