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Qian L, Zhu Y, Deng C, Liang Z, Chen J, Chen Y, et al

J Physiol, 591(18):4655-66

Preclinical approaches to reduce hepatotoxicity include nanoparticle encapsulation with hepatocyte-avoidant peptides, which reduce liver uptake by up to 90%, or co-administration with PPAR agonists to enhance lipid clearance [228]
