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If the liver depresses and qi stagnates, depression transforms into fire, the upward flaming of the liver fire invades the descending of the lung qi (), which is characterized by a burning pain in the chest and subcostal region, restlessness, irritability, a dry and bitter mouth, paroxysmal coughs, and even hemoptysis

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In the early 2000s, the company held two early-stage trials to see if BPC-157 could help treat ulcerative colitis