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Notably, the clinical phase III trial testing the therapeutic effect of Bardoxolone methyl, a potent Nrf2 activator, on chronic renal disease associated with type 2 diabetes was terminated because of an increased rate of cardiovascular events, including heart failure and deaths (Ouyang et al., 2014

L Glutathione is a naturally occurring tripeptide of glutamine, cysteine, and glycine, known for its antioxidant and detoxifying properties

CTR1 was co-localized with -SMA in NRK-49F cells after TGF-1 treatment by Immunofluorescence staining (Fig

6g), along with the spleen size (Fig
