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VGF is a neurosecretory protein that primarily functions via its downstream proteoforms, with putative roles in metabolic regulation, A clearance and synaptogenesis 48,49,50
In addition, the upregulation of antioxidant enzymes by Nrf2 activation helps to reduce inflammation, a condition often exacerbated by chronic metabolic disorders
Prion-like acceleration of a synucleinopathy in a transgenic mouse model
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