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125 Additionally, CSCs interact with their microenvironment through secreted factors, such as cytokines and extracellular vesicles (e.g., exosome-derived miRNAs), further expanding the repertoire of potential biomarkers 126 (Fig
Flux across the pore and leak pathways reflects permeability of tight junctions, which seal the space between adjacent epithelial cells and are the rate-limiting components of paracellular transport
The transcription factor IRF4 is essential for TCR affinitymediated metabolic programming and clonal expansion of T cells
Iida et al., 1999)
