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Homocysteine Homocysteine is another way to assess Vitamin B12 levels, it is not as specific as MMA because high homocysteine levels can also indicate a deficiency in B2, B6, folate, and B12

This interaction prevents actin polymerization and promotes actin sequestration, thereby facilitating cellular migration and morphological changes essential for wound healing and tissue repair

Deficiency typically presents as unexplained fatigue, numbness or tingling, and macrocytic anemia

In general, albeit not always, iron deficiency leads to microcytosis whereas vitamin B 12 and folate deficiencies result in macrocytosis (Green, 12 combined anemia (Remacha et al., 2013)