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Ten genes (CXCL1, FCAR, CKAP4, SPINK4, CXCL17, OSM, CD4, CXCL9, IL17A, and GZMB) exhibited significant alterations from baseline in responders compared to non-responders at week 8, particularly in terms of endoscopic improvement or histological remission

Our findings demonstrated that glutathione acts as a sulfur-donating metabolite for a previously unknown transsulfuration reaction with the metabolite -Glu-Ser-Gly being biosynthesized

Increased methylation of the MOR gene proximal promoter in primary sensory neurons plays a crucial role in the decreased analgesic effect of opioids in neuropathic pain

A.LoftM.LoftA.BerthelsenA
