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Kolberg M, Holand M, Agesen TH, Brekke HR, Liestol K, Hall KS, et al

Honest suitability guidance is always given at consultation
After 4 weeks diet, POMC and AgRP mRNA levels were not different between diet groups
While overall decline rates were similar between groups, post-hoc subgroup analysis indicated slower cognitive decline in early-onset patients (aged 65 or younger) compared to placebo, as measured by the Alzheimer's Disease Assessment Scale cognitive subscale and Clinical Dementia Rating Scale [5][18]