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In the GHK-Cu complex, the copper ion coordinates with multiple binding sites: the nitrogen from the histidine imidazole side chain, the alpha-amino group of glycine, the deprotonated amide nitrogen of the glycine-histidine peptide bond, and oxygen from the lysine carboxyl group, forming a square-planar pyramid configuration

Ans :- Most side effects are mild and last between a few hours and 48 hours

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[181] Infections such as cellulitis and sepsis may result from lymphedema due to the dense protein rich nature of the lymphatic fluid and requires treatment with antibiotics