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170175 Wang et al
2021;12 doi: 10.3389/fphar.2021.673103
NAD+ injections bypass the digestive tract, allowing NAD+ to enter systemic circulation efficiently
Correspondingly, TFs that are activated by ROS comprise Nrf2, HIF-1, AP-1, and NF-B [84, 85], some of which are discussed in this review as TFs binding to HIF1A promoter to upregulate HIF-1 at the transcriptional level
