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Another study showed that calmangafodipir protected against small fiber neuropathy in an oxaliplatin-induced BALB/c mouse model, and interestingly, in addition to consistent with previous findings, calmangafodipir showed a U-shaped effect, with the 10 mg/kg dose less effective than the 2.5 and 10 mg/kg doses [156]
Environ Res 107:4552 Clarkson TW (1972) The pharmacology of mercury compounds
The functions of the receptors/proteins involved in ubiquitinylation, several protein kinases and transcription factors can be altered upon formation of mixed disulfides
