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Recent studies have validated exogenous MG53 (1 mg/kg, single-dose) has been shown to preserve mitochondrial integrity during I/R-induced oxidative stress via binding to the mitochondria-specific phospholipid cardiolipin (CL), thereby preventing ROS and mitophagy for cardioprotection [153]
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Confidence in NMA results ranged between moderate and high (online supplemental appendix 17)
This is important to the unimpeded flow of the Antarctic Circumpolar Current, which carries a huge volume of water (about 600 times the flow of the Amazon River) through the passage and around Antarctica
