glutathione reductase and thiredoxin reductase Thioredoxin from Schistosoma mansoni: An Essential Parasite Enzyme a Key Drug Target Thioredoxin and glutathione reductases -
Description
The transcription factor ATF4 in turn activates stress-responsive genes such as Tribbles homolog 3 (Trib3) and solute carrier family 7 member 11 (Slc7A11) to mediate protective effects of the integrative stress response 16

The therapeutic promise of AST lies not only in its molecular potency but also in its potential integration into multi-target interventions for complex neurodegenerative disorders

Reversing the Warburg effect as a treatment for glioblastoma

Gerontology 65, 513523
