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Its name originates from studies on maternal-fetal and maternal-neonatal transmission of Ab immunity [15,16,17,18] and subsequent identification of the receptor itself in the intestinal epithelium of neonatal rodents [19], which at the time pointed to a role predominantly in the early stages of life

The beneficial significance of the egr-1 gene implies the healing process (i.e., trans-activation of many cognate target genes in healing tissue, including growth factors and cytokines (Braddock et al., 1999
