glutathione-reactive substances Glutathione-Mediated Conjugation of Anticancer Drugs: An Overview of Reaction Mechanisms and Biological Significance for Drug Detoxification and Bioactivation Frontiers | Research progress of
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The irreversibility of this reaction, together with the absence of alternative pathways, explains why acetyl-CoA, and therefore fatty acids, cannot be used as substrates for gluconeogenesis

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Genotoxicity studies with paracetamol
