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This approach significantly suppresses tissue damage caused by OxS in T2DM patients [38]
A possible hypothesis is that, as GSH is a substrate of GSH-Px, high GSH levels could be a consequence of the increase in oxidative stress induced by a reduction of GSH-Px activity
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Discuss with patients or their caregiver(s) about the importance of monitoring of liver-related tests before taking JUXTAPID, prior to each dose escalation, and periodically thereafter
