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Synthesis of Results The primary meta-analysis pooled all RCTs across depression rating scales using standardized mean difference (SMD) random effects (REML)

Non-pharmacological approaches involve addressing the underlying causes of cirrhosis and adhering to the validated TrACE (Treating causes, Ameliorating modifiable factors, Coping mechanisms, and Empathizing) model, particularly used to manage fatigue in primary biliary cholangitis

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Interestingly, swim speeds of day 2, 3 and 5 showed significant correlations with muscle fiber diameter (P-values of 0.046, 0.06 and 0.078 respectively), while heart rate exhibited a negative correlation with swim speed, although not statistically significant