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The threshold for squeezing unmethylated DNA through 1.8 nm pore is about 3.6 V while fully-methylated DNA shows a threshold 2.7 V
doi: 10.1016/j.fertnstert.2022.04.028 6 KesariKKAgarwalAHenkelR
However, due to the existence of drug resistance mechanism of tumor cells, the efficacy of chemotherapeutic drugs will also be affected by drug resistance during the treatment of gastric cancer patients [5]
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